INSIG1 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA011745LA01HU-50UG
100 ug
£334,00
CSB-PA011745LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA011745LA01HU
- Zusätzliche Namen:
- CL 6 antibody; CL6 antibody; INSI1_HUMAN antibody; INSIG 1 antibody; INSIG 1 membrane protein antibody; INSIG-1 antibody; insig1 antibody; INSIG1 membrane protein antibody; Insulin induced gene 1 antibody; Insulin induced gene 1 protein antibody; Insulin-induced gene 1 protein antibody; MGC1405 antibody
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May play a regulatory role during G0/G1 transition of cell growth.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Insulin-induced gene 1 protein (1-87AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:INSIG1-Antibody-12555957.html
