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Antikörper

IFITM3 Antibody, Biotin conjugated

Produktgrößen
50 ug
£186,00
CSB-PA011026LD01HU-50UG
100 ug
£334,00
CSB-PA011026LD01HU-100UG
Über dieses Produkt
SKU:
CSB-PA011026LD01HU
Zusätzliche Namen:
1 8U antibody; Fragilis antibody; IFITM3 antibody; IFM3_HUMAN antibody; Interferon induced transmembrane protein 3 (1 8U) antibody; Interferon Induced Transmembrane Protein 3 antibody; Interferon inducible antibody; Interferon inducible protein 1 8U antibody; Interferon Inducible Protein 15 antibody; Interferon Inducible Protein Homolog antibody; Interferon-induced transmembrane protein 3 antibody; Interferon-inducible protein 1-8U antibody; IP15 antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Klonalität:
Polyclonal
Konjugat:
Biotin
Weitere Details:
IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
Host:
Rabbit
Immunogen:
Recombinant Human Interferon-induced transmembrane protein 3 protein (1-57AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody