HSPA1L Antibody, Biotin conjugated
Produktgrößen
50 ul
£186,00
CSB-PA010823HD01HU-50UL
100 ul
£334,00
CSB-PA010823HD01HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA010823HD01HU
- Zusätzliche Namen:
- Heat shock 70 kDa protein 1 Hom antibody; Heat shock 70 kDa protein 1 like antibody; Heat shock 70 kDa protein 1-Hom antibody; Heat shock 70 kDa protein 1-like antibody; Heat shock 70 kDa protein 1L antibody; Heat shock 70kD protein like 1 antibody; HS71L_HUMAN antibody; HSP70 1L antibody; HSP70 HOM antibody; HSP70-Hom antibody; HSPA1L antibody; hum70t antibody; Spermatid specific heat shock protein 70 antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed:26865365). Positive regulator of PRKN translocation to damaged mitochondria (PubMed:24270810).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Heat shock 70 kDa protein 1-like protein (420-641AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:HSPA1L-Antibody--Biotin-conjugated-12925828.html