H2AFX (Ab-142) Antibody
Produktgrößen
50 ul
£186,00
CSB-PA010097PA142NPHHU-50UL
100 ul
£334,00
CSB-PA010097PA142NPHHU-100UL
Über dieses Produkt
- SKU:
- CSB-PA010097PA142NPHHU
- Zusätzliche Namen:
- Histone H2AX (H2a/x) (Histone H2A.X), H2AFX, H2AX
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human Histone H2AX protein (130-142aa)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:H2AFX--Ab-142--Antibody-12930661.html
