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Antikörper

GZMA Antibody

Produktgrößen
50 ul
£186,00
CSB-PA010081ESR2HU-50UL
100 ul
£334,00
CSB-PA010081ESR2HU-100UL
Über dieses Produkt
SKU:
CSB-PA010081ESR2HU
Zusätzliche Namen:
CTL tryptase antibody; CTLA3 antibody; Cytolytic t cell and natural killer cell specific trypsin like serine protease antibody; Cytotoxic T lymphocyte associated serine esterase 3 antibody; Cytotoxic T lymphocyte proteinase 1 antibody; Cytotoxic T-lymphocyte proteinase 1 antibody; Fragmentin 1 antibody; Fragmentin-1 antibody; GRAA_HUMAN antibody; Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3 antibody; Granzyme A (Cytotoxic T lymphocyte associated serine esterase 3, Hanukah factor serine protease) antibody; Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3) antibody; Granzyme A antibody; Granzyme A precursor antibody; Granzyme-1 antibody; GZMA antibody; H factor antibody; Hanukah factor serine protease antibody; Hanukkah factor antibody; HF antibody; HFSP antibody; TSP1 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Host:
Rabbit
Immunogen:
Recombinant Human Granzyme A protein (29-262AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody