GRIA3 Antibody
Produktgrößen
100 ul
£445,00
CSB-PA009900KA01HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA009900KA01HU
- Zusätzliche Namen:
- AMPA 3 antibody; AMPA selective glutamate receptor 3 antibody; AMPA-selective glutamate receptor 3 antibody; dJ1171F9.1 antibody; GluA3 antibody; GLUK3 antibody; GluR 3 antibody; GLUR C antibody; GLUR K3 antibody; GluR-3 antibody; GluR-C antibody; GluR-K3 antibody; GLUR3 antibody; GLURC antibody; Glutamate ionotropic receptor AMPA type subunit 3 antibody; Glutamate receptor 3 antibody; Glutamate receptor C antibody; Glutamate receptor ionotrophic AMPA 3 antibody; Glutamate receptor ionotropic antibody; Glutamate receptor subunit 3 antibody; Glutamate receptor; ionotropic; AMPA 3 antibody; GRIA 3 antibody; Gria3 antibody; GRIA3_HUMAN antibody; Ionotrophic Glutamate Receptor antibody; MRX94 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Klonalität:
- Polyclonal
- Weitere Details:
- AMPA- (A Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainite- and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Post-transcriptional modifications (alternative splicing and nuclear RNA editing) and post-translational modifications (glycosylation, phoshorylation) result in a very large number of permutations, fine-tuning the kinetic properties of AMPARs. GluR 3 knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR 3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Retts syndrome, amyotrophic lateral sclerosis and Alzheimer disease.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of Human GRIA3
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:GRIA3-Antibody-1035607.html
