FZD7 Antibody, FITC conjugated
Produktgrößen
50 ul
£186,00
CSB-PA009110LC01HU-50UL
100 ul
£334,00
CSB-PA009110LC01HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA009110LC01HU
- Zusätzliche Namen:
- Frizzled 7; seven transmembrane spanning receptor antibody; frizzled class receptor 7 antibody; Frizzled drosophila homolog of 7 antibody; Frizzled family receptor 7 antibody; Frizzled homolog 7 antibody; Frizzled-7 antibody; Frizzled7 antibody; Fz 7 antibody; Fz-7 antibody; Fz7 antibody; FZD 7 antibody; FZD7 antibody; FZD7_HUMAN antibody; FzE 3 antibody; FzE3 antibody; hFz 7 antibody; hFz7 antibody; Homolog of Drosophila Frizzled 7 antibody; OTTHUMP00000163742 antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- FITC
- Weitere Details:
- Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Frizzled-7 protein (161-239AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:FZD7-Antibody--FITC-conjugated-12925815.html