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Antikörper

EPHB4 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA007732ESR2HU-50UL
100 ul
£334,00
CSB-PA007732ESR2HU-100UL
Über dieses Produkt
SKU:
CSB-PA007732ESR2HU
Zusätzliche Namen:
Ephb4 antibody; EPHB4_HUMAN antibody; Ephrin receptor EphB4 antibody; Ephrin type-B receptor 4 antibody; Hepatoma Transmembrane Kinase antibody; HTK antibody; MYK 1 antibody; MYK1 antibody; TYRO 11 antibody; TYRO11 antibody; Tyrosine-protein kinase receptor HTK antibody; Tyrosine-protein kinase TYRO11 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
Host:
Rabbit
Immunogen:
Recombinant Human Ephrin type-B receptor 4 protein (300-540AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody