EIF3E Antibody
Produktgrößen
50 ul
£186,00
CSB-PA007534ESR1HU-50UL
100 ul
£334,00
CSB-PA007534ESR1HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA007534ESR1HU
- Zusätzliche Namen:
- eIF-3 p48 antibody; eIF3e antibody; EIF3E_HUMAN antibody; EIF3S6 antibody; eIFe antibody; Eukaryotic translation initiation factor 3 subunit 6 antibody; Eukaryotic translation initiation factor 3 subunit E antibody; eukaryotic translation initiation factor 3; subunit 6 (48kD) antibody; INT6 antibody; mammary tumor-associated protein INT6 antibody; murine mammary tumor integration site 6 (oncogene homolog) antibody; Viral integration site protein INT-6 homolog antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Eukaryotic translation initiation factor 3 subunit E protein (1-445AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:EIF3E-Antibody-1091894.html
