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Antikörper

DVL2 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA007286ESR1HU-50UL
100 ul
£334,00
CSB-PA007286ESR1HU-100UL
Über dieses Produkt
SKU:
CSB-PA007286ESR1HU
Zusätzliche Namen:
Dishevelled 2 (homologous to Drosophila dsh) antibody; Dishevelled dsh homolog 2 antibody; dishevelled segment polarity protein 2 antibody; Dishevelled-2 antibody; Dishevelled2 antibody; DSH homolog 2 antibody; DVL 2 antibody; Dvl2 antibody; DVL2_HUMAN antibody; Segment polarity protein dishevelled homolog DVL 2 antibody; Segment polarity protein dishevelled homolog DVL-2 antibody; Segment polarity protein dishevelled homolog DVL2 antibody
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes .
Host:
Rabbit
Immunogen:
Recombinant Human Segment polarity protein dishevelled homolog DVL-2 protein (1-240AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA007286ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007286ESR1HU at dilution of 1:100
Immunofluorescence staining of A549 cells with CSB-PA007286ESR1HU at 1:75, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
IHC image of CSB-PA007286ESR1HU diluted at 1:227 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA007286ESR1HU diluted at 1:227 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.