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Antikörper

CXADR Antibody

Produktgrößen
50 ug
£186,00
CSB-PA006237LA01HU-50UG
100 ug
£334,00
CSB-PA006237LA01HU-100UG
Über dieses Produkt
SKU:
CSB-PA006237LA01HU
Zusätzliche Namen:
46 kD coxsackievirus and adenovirus receptor CAR protein antibody; 46 kD coxsackievirus and adenovirus receptor protein antibody; CAR antibody; CAR4/6 antibody; Coxsackie virus and adenovirus receptor antibody; Coxsackie virus B receptor antibody; Coxsackievirus and adenovirus receptor antibody; Coxsackievirus B adenovirus receptor antibody; Coxsackievirus B-adenovirus receptor antibody; CVB3 binding protein antibody; CVB3-binding protein antibody; Cxadr antibody; CXADR Ig like cell adhesion molecule antibody; CXAR_HUMAN antibody; hCAR antibody; HCVADR antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Weitere Details:
Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
Host:
Rabbit
Immunogen:
Recombinant Human Coxsackievirus and adenovirus receptor protein (259-365AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody