CNOT1 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA005663LA01HU-50UG
100 ug
£334,00
CSB-PA005663LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA005663LA01HU
- Zusätzliche Namen:
- CNOT1 antibody; CDC39 antibody; KIAA1007 antibody; NOT1 antibody; AD-005CCR4-NOT transcription complex subunit 1 antibody; CCR4-associated factor 1 antibody; Negative regulator of transcription subunit 1 homolog antibody; NOT1H antibody; hNOT1 antibody
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of emryonic stem (ES) cell identity.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CCR4-NOT transcription complex subunit 1 protein (604-867AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CNOT1-Antibody-12255485.html
