CH25H Antibody, FITC conjugated
Produktgrößen
50 ug
£186,00
CSB-PA005307LC01HU-50UG
100 ug
£334,00
CSB-PA005307LC01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA005307LC01HU
- Zusätzliche Namen:
- CH25H antibody; Cholesterol 25-hydroxylase antibody; EC 1.14.99.38 antibody; Cholesterol 25-monooxygenase antibody; h25OH antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- FITC
- Weitere Details:
- Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cholesterol 25-hydroxylase protein (142-272AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CH25H-AntibodyFITC-conjugated-12553392.html