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Antikörper

CEP290 Antibody, FITC conjugated

Produktgrößen
50 ug
£186,00
CSB-PA005241LC01HU-50UG
100 ug
£334,00
CSB-PA005241LC01HU-100UG
Über dieses Produkt
SKU:
CSB-PA005241LC01HU
Zusätzliche Namen:
3H11AG antibody; Bardet-Biedl syndrome 14 protein antibody; BBS14 antibody; Cancer/testis antigen 87 antibody; CE290_HUMAN antibody; Centrosomal protein 290 antibody; Centrosomal protein 290kDa antibody; Centrosomal protein of 290 kDa antibody; Cep290 antibody; CT87 antibody; CTCL tumor antigen se2 2 antibody; FLJ13615 antibody; FLJ21979 antibody; JBTS5 antibody; JBTS6 antibody; KIAA0373 antibody; LCA10 antibody; Meckel syndrome; type 4 antibody; MKS4 antibody; Monoclonal antibody 3H11 antigen antibody; Nephrocystin 6 antibody; Nephrocystin-6 antibody; NPHP6 antibody; POC3 antibody; POC3 centriolar protein homolog antibody; Prostate cancer antigen T21 antibody; rd16 antibody; SLSN6 1; 2; 5 antibody; SLSN6 antibody; Tumor antigen se2-2 antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
FITC
Weitere Details:
Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110 (PubMed:18694559). May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1 (PubMed:24421332). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2, BBS5 and BBS8/TTC8 in the complex, and in ciliary targeting of selected BBSome cargos. May act as a gatekeeper to control entry of the BBSome complex to cilia (PubMed:25552655). Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes (By similarity). Activates ATF4-mediated transcription (PubMed:16682973).
Host:
Rabbit
Immunogen:
Recombinant Human Centrosomal protein of 290 kDa protein (86-156AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody