CBFA2T2 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA004575ESR2HU-50UL
100 ul
£334,00
CSB-PA004575ESR2HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA004575ESR2HU
- Zusätzliche Namen:
- AML1 MTG8 antibody; cbfa2t2 antibody; Core binding factor runt domain alpha subunit 2 translocated to 2 antibody; core-binding factor; runt domain; alpha subunit 2 antibody; DKFZp313F2116 antibody; EHT antibody; ETO homolog on chromosome 20 antibody; ETO homologous on chromosome 20 antibody; MTG 8 like protein antibody; MTG 8 related protein 1 antibody; MTG8 like protein antibody; MTG8 related protein 1 antibody; MTG8-like protein antibody; MTG8-related protein 1 antibody; MTG8R_HUMAN antibody; MTGR 1 antibody; Myeloid translocation gene related protein 1 antibody; Myeloid translocation related protein 1 antibody; Myeloid translocation-related protein 1 antibody; p85 antibody; Protein CBFA2T2 antibody; ZMYND 3 antibody; ZMYND3 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Protein CBFA2T2 protein (325-604AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CBFA2T2-Antibody-11909060.html
