AURKC Antibody, HRP conjugated
Produktgrößen
50 ug
£186,00
CSB-PA002460LB01HU-50UG
100 ug
£334,00
CSB-PA002460LB01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA002460LB01HU
- Zusätzliche Namen:
- AURKC antibody; AIE 2 antibody; Aie1 antibody; AIE2 antibody; AIK 3 antibody; AIK3 antibody; ARK 3 antibody; ARK-3 antibody; ARK3 antibody; Aur C antibody; AurC antibody; Aurkc antibody; AURKC_HUMAN antibody; aurora 3 antibody; Aurora C antibody; Aurora kinase C antibody; aurora related kinase 3 antibody; Aurora-related kinase 3 antibody; Aurora/Ipl1 related kinase 3 antibody; Aurora/Ipl1-related kinase 3 antibody; Aurora/Ipl1/Eg2 protein 2 antibody; EC 2.7.11.1 antibody; Serine threonine protein kinase 13 antibody; serine/threonine kinase 13 (aurora/IPL1 like) antibody; serine/threonine protein kinase aurora C antibody; Serine/threonine-protein kinase 13 antibody; Serine/threonine-protein kinase aurora-C antibody; SPGF5 antibody; STK13 antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- HRP
- Weitere Details:
- Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Aurora kinase C protein (12-143AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:AURKC-AntibodyHRP-conjugated-12555882.html