ALOX12 Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA001617LD01HU-50UG
100 ug
£334,00
CSB-PA001617LD01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA001617LD01HU
- Zusätzliche Namen:
- 12 LOX antibody; 12(S) lipoxygenase antibody; 12-lipoxygenase antibody; 12LO antibody; 12S LOX antibody; 12S-lipoxygenase antibody; 12S-LOX antibody; 12S-type antibody; Alox12 antibody; Arachidonate 12 lipoxygenase antibody; Arachidonate 12 lipoxygenase, 12S type antibody; Arachidonate 12-lipoxygenase antibody; Arachidonate 12-oxidoreductase antibody; Lipoxin synthase 12-LO antibody; LOG12 antibody; LOX12_HUMAN antibody; P-12LO antibody; Platelet 12-LOX antibody; Platelet type lipoxygenase 12 antibody; platelet-type 12-lipoxygenase antibody; Platelet-type lipoxygenase 12 antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Arachidonate 12-lipoxygenase, 12S-type protein (508-658AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:ALOX12-Antibody-Biotin-conjugated-12919283.html