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Antikörper

GRB2 Monoclonal Antibody

Produktgrößen
100 ul
£429,00
CSB-MA148138-100UL
Über dieses Produkt
SKU:
CSB-MA148138
Zusätzliche Namen:
Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3
Anwendung:
ELISA, Western Blot
Klonalität:
Monoclonal
Weitere Details:
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Host:
Mouse
Immunogen:
Purified recombinant human GRB2 protein fragments expressed in E.coli.
Isotyp:
IgG1
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Non-human Primate, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Monoclonal Antibody