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Antikörper

APP Monoclonal Antibody

Produktgrößen
50 ug
£235,00
CSB-MA0019501A0M-50UG
100 ug
£392,00
CSB-MA0019501A0M-100UG
Über dieses Produkt
SKU:
CSB-MA0019501A0M
Zusätzliche Namen:
Amyloid Beta (A4) Precursor Protein, ABPP, APP, Beta-Amyloid Peptide
Anwendung:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
translate.label.attr.clone:
5A11E5
Klonalität:
Monoclonal
Weitere Details:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Host:
Mouse
Immunogen:
Recombinant Human APP Protein
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Monoclonal Antibody