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Antikörper

PCNA Monoclonal Antibody

Produktgrößen
50 ug
£193,00
CSB-MA000081M0M-50UG
100 ug
£224,00
CSB-MA000081M0M-100UG
Über dieses Produkt
SKU:
CSB-MA000081M0M
Zusätzliche Namen:
Cyclin, PCNA
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
translate.label.attr.clone:
3C33G3
Klonalität:
Monoclonal
Weitere Details:
Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase D Delta in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution; the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells. This antibody is a rabbit polyclonal antibody raised against an internal region of human PCNA.
Host:
Mouse
Immunogen:
PCNA fusion protein
Isotyp:
IgG1
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Wide/Non-species Specific
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Monoclonal Antibody