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Proteine und Peptide

Human Interleukin 1 Beta (IL1b), Active Protein

Produktgrößen
50 ug
£1036,00
RPU54844-50UG
100 ug
£1410,00
RPU54844-100UG
1 mg
£6180,00
RPU54844-1MG
Über dieses Produkt
SKU:
RPU54844
Zusätzliche Namen:
Catabolin|IL-1B Beta|IL1-B|IL1-Beta|IL1F2|Interleukin-1 Family Member 2
Anwendung:
Detection/Quantitation, Tissue Culture
Buffer:
Freeze-dried powder|PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
CE/IVD:
RUO
Weitere Details:
Human Interleukin 1 Beta (IL1b), Active Protein is a purified Prokaryotic Protein.
Formulierung:
Freeze-dried powder
Immunogen:
Interleukin 1 Beta (IL1b)
Molekulargewicht:
21kDa
Physischer Zustand:
freeze-dried
Reinheit:
>95%
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Biomatik
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Catalog Protein.JPG
Active Interleukin 1 Beta (IL1b), RPU54844
IL-1B Beta (Interleukin-1 beta) is a proinflammatory and immunoregulatory cytokine involved in a variety of cellular activities. It is produced by activated macrophages as a proprotein, and then proteolytically processed to an active form. It has been reported that IL-1B Beta-induced IL-6 production is mediated by both PI3K and IRAK4 in A549 cells. To detect the bioactivity of IL-1B Beta, A549 cells were seeded into 24-well plate at a density of 1x105cells/mL, and allowed to attach overnight before treated with or without certain concentrations (1ng/mL, 10ng/mL) of IL1-B Beta for 4h and IL-6 levels in the cell supernatant were determined by ELISA. IL-6 levels in the cell supernatant of A549 cells increased significantly after stimulated with IL1-B Beta, the data was shown in Table 1 and Figure 1.