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Proteine und Peptide

Human Osteopontin (OPN), Active Protein

Produktgrößen
50 ug
£355,00
RPU54834-50UG
100 ug
£527,00
RPU54834-100UG
1 mg
£1757,00
RPU54834-1MG
Über dieses Produkt
SKU:
RPU54834
Zusätzliche Namen:
BNSP|Bone Sialoprotein I|BSPI|Early T-Lymphocyte Activation 1|ETA1|Nephropontin|Secreted Phosphoprotein 1|SPP1|Urinary stone protein|Uropontin
Anwendung:
Detection/Quantitation, Tissue Culture
Buffer:
Freeze-dried powder|PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
CE/IVD:
RUO
Weitere Details:
Human Osteopontin (OPN), Active Protein is a purified Eukaryotic Protein.
Formulierung:
Freeze-dried powder
Immunogen:
Osteopontin (OPN)
Molekulargewicht:
60kDa
Physischer Zustand:
freeze-dried
Reinheit:
>95%
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Biomatik
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Catalog Protein.JPG
Active Osteopontin (OPN), RPU54834
Osteopontin (OPN), a multifunctional phosphorylated glycoprotein, plays an important role in neutrophil recruitment and was found to induce the expression of proinflammatory chemokines including MCP-1 and MIP-1B Beta which would promote migration and recruitment of inflammatory cells. It has been reported that OPN induces MCP-1 expression through the NF-kappa B pathways in MCF-7 breast cancer cell line. Briefly, MCF-7 cells were seeded overnight at a density of 1x105 cells/mL, and treated with or without OPN(100ng/ml,200ng/ml) for 24h and MCP-1 levels in the cell supernatant were determined by ELISA. MCP-1 levels in the cell supernatant of MCF-7 cells increased significantly after stimulated with OPN, the data was shown in Table 1 and Figure 1.