ENSA Protein
Produktgrößen
5µg
£186,00
OPPA02085-5UG
Über dieses Produkt
- SKU:
- OPPA02085
- Zusätzliche Namen:
- ARPP-19e
- Weitere Details:
- ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor and thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein (ARPP) family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor; ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle; brain; and endocrine tissues.
- Host:
- E. coli
- Proteindetails:
- Alpha-endosulfine
- Reinheit:
- Greater than 90.0% as determined by SDS-PAGE.
- Aufreinigung:
- The ENSA is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C if entire vial will be used within 2-4 weeks. Store; frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:html_datasheet.php