Fibronectin Human - Human Fibronectin Protein
Produktgrößen
200µg
£207,00
OPPA01778-200UG
Über dieses Produkt
- SKU:
- OPPA01778
- Zusätzliche Namen:
- FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF
- Konzentration:
- 2 mg/ml (prior to lyophilization)
- Weitere Details:
- Plasma fibronectin level is elevated in severe coronary artery disease. Increased plasma fibronectin levels are related with venous thromboembolism (VTE) particularly in males; and extend the probable association between biomarkers and risk factors for arterial atherothrombosis and VTE. Fibronectin plays a role in several cellular processes; including tissue repair; embryogenesis; blood clotting; and cell migration/adhesion. Fibronectin consists in two main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the etracellular matrix and 2) as a soluble disulphide linked dimer found in the plasma. The plasma form is produced by hepatocytes; and the ECM form is synthesized by fibroblasts; chondrocytes; endothelial cells; macrophages; as well as certain epithelial cells. Fibronectin alos takes part as a general cell adhesion molecule by anchoring cells to collagen or proteoglycan substrates. Fibronectin organizes cellular interaction with the ECM by binding to different components of the extracellular matrix and to membrane-bound Fibronectin receptors on cell surfaces.
- Molekulargewicht:
- 440 kDa
- Proteindetails:
- Fibronectin EMBL AAD00013.1
- Reinheit:
- Greater than 95.0% as determined by SDS-PAGE.
- Aufreinigung:
- Human Fibronectin produced purified from Human Plasma
- Versandbedingungen:
- Ambient
- Quelle:
- Human Plasma
- Lagerbedingungen:
- Purified fibronectin has a tendency to form insoluble aggregates upon reconstitution. We suggest reconstituting the 1mg Fibronectin with a chaotropic agent such as urea at room temperature at a concentration of 0.2 mg/ml using sterile water. Let stand 1-2 hours. The recommended concentration is 4M-5M urea. When using the protein as an attachment factor; wash the urea off after attaching the fibronectin to the growth surface (plate or dish). Store the lyophilized fibronectin at 4°C. Upon reconstitution fibronectin should be store at 4°C for 2 weeks and for future use below -18°C.
Please prevent multiple freeze-thaw cycles. - Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:html_datasheet.php