GPBB Protein
Produktgrößen
5µg
£186,00
OPPA00804-5UG
Über dieses Produkt
- SKU:
- OPPA00804
- Zusätzliche Namen:
- GPBB
- Weitere Details:
- Glycogen phosphorylase is one of the phosphorylaseenzymes(EC2.4.1.1). It breaks up glycogeninto glucosesubunits. Glycogenis left with one less glucosemolecule; and the free glucosemolecule is in the form of glucose-1-phosphate. In order to be used for metabolism; it must be converted to glucose-6-phosphateby the enzyme phosphoglucomutase. Glycogen phosphorylase can only act on linearchainsof glycogen(a 1-4 glycosidic linkage). Its work will immediately come to a halt four residues away from a 1-6 branch(which are exceedingly common in glycogen). In these situations; a debranching enzymeis necessary; which will straighten out the chain in that area. Additionally; an alpha 1-6 glucosidaseenzymeis required to break the remaining 1-6 residue that remains in the new linear chain. After all this is done; glycogen phosphorylase can continue. An insulinstimulated enzyme known as phosphoprotein phosphatase(PP-1) inactivates glycogen phosphorylase to prevent glycogen break up. GPBB - a sensitive marker for the AMI diagnosis within 4 hours after the onset of chest pain. It has also been shown that GPBB is increased in a considerable proportion of AMI patients within 2-3 hours from chest pain onset. GPBB is increased early in patients with unstable angina. GPBB can also be a sensitive marker for the detection of peri-operative myocardial ischaemia and infarction in patients undergoing coronary artery bypass grafting.
- Molekulargewicht:
- 96695.96 Dalton
- Proteindetails:
- Glycogen phosphorylase; brain form
- Reinheit:
- Greater than 85.0% as determined by:<br> (a) Analysis by RP-HPLC<br>(b) Analysis by SDS-PAGE.
- Aufreinigung:
- The GPBB is purified by proprietary chromatographic techniques.
- Versandbedingungen:
- Blue Ice
- Quelle:
- Escherichia Coli
- Lagerbedingungen:
- GPBB although stable at 10°C for 7 days; should be stored below -18°C .
Please prevent freeze-thaw cycles. - Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:html_datasheet.php