EBI3 Recombinant Protein
Produktgrößen
10 ug
£727,00
OPED00077-10UG
Über dieses Produkt
- SKU:
- OPED00077
- Zusätzliche Namen:
- CLMF;CLMF p35;cytokine receptor;cytotoxic lymphocyte maturation factor 1; p35;cytotoxic lymphocyte maturation factor 35 kDa subunit;EBV-induced gene 3 protein;Epstein-Barr virus induced gene 3;epstein-Barr virus-induced gene 3 protein;IL-12 subunit p35;IL-12; subunit p35;IL-12A;IL27 subunit;IL-27 subunit beta;IL27B;IL-27B;IL35 subunit;IL35B;interleukin 12; p35;interleukin 12A (natural killer cell stimulatory factor 1; cytotoxic lymphocyte maturation factor 1; p35);interleukin-12 alpha chain;interleukin-12 subunit alpha;interleukin-27 subunit beta;NF cell stimulatory factor chain 1;NFSK;NK cell stimulatory factor chain 1;NKSF1;P35.
- Weitere Details:
- Associates with IL27 to form the IL-27 interleukin; a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties; that can regulate T-helper cell development; suppress T-cell proliferation; stimulate cytotoxic T-cell activity; induce isotype switching in B-cells; and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1); type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells; binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.|Cytokine that can act as a growth factor for activated T and NK cells; enhance the lytic activity of NK/lymphokine-activated Killer cells; and stimulate the production of IFN-gamma by resting PBMC.
- Gendetails:
- Epstein-Barr virus induced 3|interleukin 12A
- Molekulargewicht:
- 85 kDa
- Proteindetails:
- Interleukin-12 subunit alpha|Interleukin-27 subunit beta
- Reinheit:
- >95% (SDS-PAGE)
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Reconstitute with 100 ul sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. Store at -20C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php