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Proteine und Peptide

FASLG Recombinant Protein

Produktgrößen
10 ug
£485,00
OPED00043-10UG
Über dieses Produkt
SKU:
OPED00043
Zusätzliche Namen:
ALPS1B;apoptosis (APO-1) antigen ligand 1;apoptosis antigen ligand;APT1LG1;APTL;CD178;CD95 ligand;CD95L;CD95-L;fas antigen ligand;Fas ligand (TNF superfamily; member 6);FASL;mutant tumor necrosis factor family member 6;TNFSF6;TNLG1A;tumor necrosis factor ligand 1A;tumor necrosis factor ligand superfamily member 6.
Weitere Details:
Cytokine that binds to TNFRSF6/FAS; a receptor that transduces the apoptotic signal into cells (PubMed:26334989; PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis; natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058; PubMed:7528780; PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3; a decoy receptor that blocks apoptosis (PubMed:27806260).
Gendetails:
Fas ligand
Molekulargewicht:
32 kDa; 35 kDa (glycosylated)
Proteindetails:
Tumor necrosis factor ligand superfamily member 6
Reinheit:
>95% (SDS-PAGE)
Aufreinigung:
Purified by multi-step chromatography.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Reconstitute with 100 ul sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. Store at -20C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins