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Proteine und Peptide

CD274 Recombinant Protein

Produktgrößen
10ug
£261,00
OPCD06040-10UG
50ug
£500,00
OPCD06040-50UG
200ug
£901,00
OPCD06040-200UG
Über dieses Produkt
SKU:
OPCD06040
Zusätzliche Namen:
B7 homolog 1;B7-H;B7H1;CD274 antigen;hPD-L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;programmed cell death 1 ligand 1.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279; modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417; PubMed:28813410). Through a yet unknown activating receptor; may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).
Gendetails:
CD274 molecule
Host:
E. coli
Molekulargewicht:
32kDa
Proteindetails:
Programmed cell death 1 ligand 1
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins