CD177 Recombinant Protein
Produktgrößen
10ug
£272,00
OPCD05583-10UG
50ug
£528,00
OPCD05583-50UG
200ug
£955,00
OPCD05583-200UG
Über dieses Produkt
- SKU:
- OPCD05583
- Zusätzliche Namen:
- CD177 antigen;cell surface receptor;HNA-2a;HNA2A;human neutrophil alloantigen 2a;NB1;NB1 glycoprotein;NB1 GP;polycythemia rubra vera protein 1;PRV1;PRV-1.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18; mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (PubMed:21193407). In addition; by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (PubMed:28807980). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (PubMed:17580308). However; appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:23461681). Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (PubMed:17244676; PubMed:18462208). By displaying PRTN3 at the neutrophil cell surface; may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis (PubMed:23202369).
- Gendetails:
- CD177 molecule
- Host:
- E. coli
- Molekulargewicht:
- 21.66kDa
- Proteindetails:
- CD177 antigen
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php