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Proteine und Peptide

CSPG4 Recombinant Protein

Produktgrößen
10ug
£283,00
OPCD05197-10UG
50ug
£561,00
OPCD05197-50UG
200ug
£1016,00
OPCD05197-200UG
Über dieses Produkt
SKU:
OPCD05197
Zusätzliche Namen:
chondroitin sulfate proteoglycan 4;chondroitin sulfate proteoglycan NG2;HSN tumor-specific antigen;membrane-spanning proteoglycan NG2;Ng2.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors; extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4; beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42; ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
Gendetails:
chondroitin sulfate proteoglycan 4
Host:
E. coli
Molekulargewicht:
66kDa
Proteindetails:
Chondroitin sulfate proteoglycan 4
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins