EPAS1 Recombinant Protein
Produktgrößen
10ug
£268,00
OPCD03874-10UG
50ug
£517,00
OPCD03874-50UG
200ug
£929,00
OPCD03874-200UG
Über dieses Produkt
- SKU:
- OPCD03874
- Zusätzliche Namen:
- bHLHe7;bHLHe73;endothelial PAS domain-containing protein 1;EPAS-1;HIF;Hif like protein;HIF1 alpha-like factor;HIF1alpha-like factor;HIF-1-alpha-like factor;HIF-2;HIF2A;HIF2-alpha;HIF-2alpha;HIF-2-alpha;HIF-related factor;HL;HLF;HLF (HIF1alpha-like factor);HR;HRF;hypoxia inducible transcription factor 2alpha;hypoxia-inducible factor 2-alpha;mHLF;MO;MOP2.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (PubMed:26245371). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).
- Gendetails:
- endothelial PAS domain protein 1
- Host:
- E. coli
- Molekulargewicht:
- 37kDa
- Proteindetails:
- Endothelial PAS domain-containing protein 1
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php