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Proteine und Peptide

GATA4 Recombinant Protein

Produktgrößen
10ug
£268,00
OPCD03454-10UG
50ug
£511,00
OPCD03454-50UG
200ug
£918,00
OPCD03454-200UG
Über dieses Produkt
SKU:
OPCD03454
Zusätzliche Namen:
DNA-binding protein GATA-GT2;GATA-binding factor 4;transcription factor GATA-4.
Konjugat:
Unconjugated
Konzentration:
150 ug/mL (prior to lyoph)
Weitere Details:
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (By similarity). In cooperation with TBX5; it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression; while it downregulates endocardial and endothelial gene expression (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (By similarity). Required during testicular development (By similarity). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression (PubMed:15329343). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (PubMed:15329343). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme; spingosine-1-phosphate lyase (By similarity).
Gendetails:
GATA binding protein 4
Host:
E. coli
Molekulargewicht:
33kDa
Proteindetails:
Transcription factor GATA-4
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins