GATA4 Recombinant Protein
Produktgrößen
10ug
£268,00
OPCD03453-10UG
50ug
£511,00
OPCD03453-50UG
200ug
£918,00
OPCD03453-200UG
Über dieses Produkt
- SKU:
- OPCD03453
- Zusätzliche Namen:
- ASD2;GATA-binding factor 4;TACHD;TOF;transcription factor GATA-4;VSD1.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169; PubMed:27984724). In cooperation with TBX5; it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression; while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme; spingosine-1-phosphate lyase (PubMed:15734735).
- Gendetails:
- GATA binding protein 4
- Molekulargewicht:
- 30kDa
- Proteindetails:
- Transcription factor GATA-4
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php