GAPDH Recombinant Protein
Produktgrößen
10ug
£272,00
OPCD03436-10UG
50ug
£528,00
OPCD03436-50UG
200ug
£955,00
OPCD03436-200UG
Über dieses Produkt
- SKU:
- OPCD03436
- Zusätzliche Namen:
- Ga;Gapd;glyceraldehyde-3-phosphate dehydrogenase;Gm20899;peptidyl-cysteine S-nitrosylase GAPDH.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities; thereby playing a role in glycolysis and nuclear functions; respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription; RNA transport; DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1; HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
- Gendetails:
- glyceraldehyde-3-phosphate dehydrogenase|glyceraldehyde-3-phosphate dehydrogenase; pseudogene 15
- Host:
- E. coli
- Molekulargewicht:
- 26kDa
- Proteindetails:
- Glyceraldehyde-3-phosphate dehydrogenase
- Reinheit:
- > 97%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php