FZD1 Recombinant Protein
Produktgrößen
10ug
£218,00
OPCD03357-10UG
50ug
£398,00
OPCD03357-50UG
200ug
£691,00
OPCD03357-200UG
Über dieses Produkt
- SKU:
- OPCD03357
- Zusätzliche Namen:
- frizzled 1; seven transmembrane spanning receptor;frizzled family receptor 1;frizzled homolog 1;frizzled; Drosophila; homolog of; 1;frizzled-1;fz-1;fzE1;hFz1;Wnt receptor.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Receptor for Wnt proteins (PubMed:10557084). Activated by WNT3A; WNT3; WNT1 and to a lesser extent WNT2; but apparently not by WNT4; WNT5A; WNT5B; WNT6; WNT7A or WNT7B (PubMed:10557084). Contradictory results showing activation by WNT7B have been described for mouse (By similarity). Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:10557084). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins; inhibition of GSK-3 kinase; nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:10557084). A second signaling pathway involving PKC and calcium fluxes has been seen for some family members; but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway; as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
- Gendetails:
- frizzled class receptor 1
- Host:
- E. coli
- Molekulargewicht:
- 27kDa
- Proteindetails:
- Frizzled-1
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php