FLT3 Recombinant Protein
Produktgrößen
10ug
£272,00
OPCD03271-10UG
50ug
£539,00
OPCD03271-50UG
200ug
£972,00
OPCD03271-200UG
Über dieses Produkt
- SKU:
- OPCD03271
- Zusätzliche Namen:
- B230315G04;CD135;fetal liver kinase 2;FL cytokine receptor;Flk;Flk-;Flk2;Flk-2;Flt-;Flt-3;Fms-like tyrosine kinase 3;Ly72;receptor-type tyrosine-protein kinase FLT3;tyrosine-protein kinase FLT3;tyrosine-protein kinase receptor flk-2;wmf;wmfl.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation; proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1; and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases; including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES; FER; PTPN6/SHP; PTPN11/SHP-2; PLCG1; and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
- Gendetails:
- FMS-like tyrosine kinase 3
- Host:
- E. coli
- Molekulargewicht:
- 27.49kDa
- Proteindetails:
- Receptor-type tyrosine-protein kinase FLT3
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php