FLT3 Recombinant Protein
Produktgrößen
10ug
£272,00
OPCD03270-10UG
50ug
£528,00
OPCD03270-50UG
200ug
£955,00
OPCD03270-200UG
Über dieses Produkt
- SKU:
- OPCD03270
- Zusätzliche Namen:
- CD135;CD135 antigen;fetal liver kinase 2;Fetal liver kinase-2;FL cytokine receptor;FLK2;FLK-2;fms related tyrosine kinase 3;fms-like tyrosine kinase 3;growth factor receptor tyrosine kinase type III;receptor-type tyrosine-protein kinase FLT3;stem cell tyrosine kinase 1;STK1.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation; proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1; and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases; including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES; FER; PTPN6/SHP; PTPN11/SHP-2; PLCG1; and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
- Gendetails:
- fms related receptor tyrosine kinase 3
- Host:
- E. coli
- Molekulargewicht:
- 27.45kDa
- Proteindetails:
- Receptor-type tyrosine-protein kinase FLT3
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php