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Proteine und Peptide

FGA Recombinant Protein

Produktgrößen
10ug
£251,00
OPCD03170-10UG
50ug
£485,00
OPCD03170-50UG
200ug
£864,00
OPCD03170-200UG
Über dieses Produkt
SKU:
OPCD03170
Zusätzliche Namen:
Fi;Fib;fibrinogen alpha chain;fibrinogen; A alpha polypeptide.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Cleaved by the protease thrombin to yield monomers which; together with fibrinogen beta (FGB) and fibrinogen gamma (FGG); polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots (PubMed:7649481). In addition; functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization (PubMed:11389004). Was originally thought to be essential for platelet aggregation; based on in vitro studies using anticoagulated blood (PubMed:7649481). However; subsequent studies have shown that it is not absolutely required for thrombus formation in vivo (PubMed:10930441). Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway (PubMed:19332769). Maternal fibrinogen is essential for successful pregnancy (PubMed:7649481). Fibrin deposition is also associated with infection; where it protects against IFNG-mediated hemorrhage (PubMed:12629066). May also facilitate the immune response via both innate and T-cell mediated pathways (PubMed:23487423).
Gendetails:
fibrinogen alpha chain
Host:
E. coli
Molekulargewicht:
32kDa
Proteindetails:
Fibrinogen alpha chain
Reinheit:
>95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins