FCGR4 Recombinant Protein
Produktgrößen
10ug
£268,00
OPCD03144-10UG
50ug
£517,00
OPCD03144-50UG
200ug
£929,00
OPCD03144-200UG
Über dieses Produkt
- SKU:
- OPCD03144
- Zusätzliche Namen:
- 4833442P21Rik;CD16-2;Fc fragment of IgG; low affinity IIIa; receptor for (CD16); Fc fragment of IgG; low affinity III; receptor for (CD16);Fc gammaRIV;Fc receptor-like 3;Fcgam;FcgammaRIV;Fcgr;Fcgr3a;FcgRIV;Fcrl3;low affinity immunoglobulin gamma Fc region receptor III-A;low affinity immunoglobulin gamma Fc region receptor IV.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411; PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578; PubMed:17558411; PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis; antigen presentation to T cells; production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411; PubMed:18949059).
- Gendetails:
- Fc receptor; IgG; low affinity IV
- Host:
- E. coli
- Molekulargewicht:
- 40kDa
- Proteindetails:
- Low affinity immunoglobulin gamma Fc region receptor IV
- Reinheit:
- > 90%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php