EGR1 Recombinant Protein
Produktgrößen
10ug
£290,00
OPCD02875-10UG
50ug
£576,00
OPCD02875-50UG
200ug
£1048,00
OPCD02875-200UG
Über dieses Produkt
- SKU:
- OPCD02875
- Zusätzliche Namen:
- A530045N19Rik;early growth response protein 1;egr;Egr-;Egr-1;ETR10;ETR103;Krox;Krox-;Krox-1;Krox24;Krox-24;Krox-24 nuclear protein;nerve growth factor-induced protein A;NG;NGF;NGF1;NGF1-A;NGFIA;NGFI-A;TI;TIS8;transcription factor Zif268;Zen;Zenk;Zfp-;Zfp-6;Zif26;Zif268;zinc finger protein Krox-24.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Transcriptional regulator (PubMed:8336701; PubMed:8703054; PubMed:15958557). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (PubMed:8703054; PubMed:15958557; PubMed:2028256; PubMed:8939742). Binds double-stranded target DNA; irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes; and thereby plays an important role in regulating the response to growth factors; DNA damage; and ischemia (PubMed:11100120; PubMed:15958557). Plays a role in the regulation of cell survival; proliferation and cell death (PubMed:15265859; PubMed:15958557). Activates expression of p53/TP53 and TGFB1; and thereby helps prevent tumor formation (PubMed:15958557). Required for normal progress through mitosis and normal proliferation of hepatocytes after partial hepatectomy (PubMed:15265859). Mediates responses to ischemia and hypoxia; regulates the expression of proteins such as IL1B and CXCL2 that are involved in inflammatory processes and development of tissue damage after ischemia (PubMed:11100120). Regulates biosynthesis of luteinizing hormone (LHB) in the pituitary (PubMed:8703054).
- Gendetails:
- early growth response 1
- Host:
- E. coli
- Molekulargewicht:
- 22/27kDa
- Proteindetails:
- Early growth response protein 1
- Reinheit:
- > 97%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php