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Proteine und Peptide

DYRK1A Recombinant Protein

Produktgrößen
10ug
£261,00
OPCD02826-10UG
50ug
£506,00
OPCD02826-50UG
200ug
£912,00
OPCD02826-200UG
Über dieses Produkt
SKU:
OPCD02826
Zusätzliche Namen:
dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A;dual specificity tyrosine-phosphorylation-regulated kinase 1A;dual specificity YAK1-related kinase;DYRK;DYRK1;HP86;MNB;mnb protein kinase homolog hp86;MNB/DYRK protein kinase;MNBH;MRD7;protein kinase minibrain homolog;serine/threonine kinase MNB;serine/threonine-specific protein kinase.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in turn inhibits TP53 activity and apoptosis (By similarity).
Gendetails:
dual specificity tyrosine phosphorylation regulated kinase 1A
Host:
E. coli
Molekulargewicht:
37kDa
Proteindetails:
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Reinheit:
>95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins