DTX1 Recombinant Protein
Produktgrößen
10ug
£261,00
OPCD02814-10UG
50ug
£500,00
OPCD02814-50UG
200ug
£901,00
OPCD02814-200UG
Über dieses Produkt
- SKU:
- OPCD02814
- Zusätzliche Namen:
- deltex 1; E3 ubiquitin ligase;deltex homolog 1;E3 ubiquitin-protein ligase DTX1;hDx-1;protein deltex-1;RING-type E3 ubiquitin transferase DTX1;RNF140.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Functions as a ubiquitin ligase protein in vivo; mediating ubiquitination and promoting degradation of MEKK1; suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling; a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch; but it also acts as a negative regulator; depending on the developmental and cell context. Mediates the antineural activity of Notch; possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis; lymphogenesis and myogenesis; and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development; suggesting that it can antagonize NOTCH1.
- Gendetails:
- deltex E3 ubiquitin ligase 1
- Host:
- E. coli
- Molekulargewicht:
- 30.26kDa
- Proteindetails:
- E3 ubiquitin-protein ligase DTX1
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php