DKK1 Recombinant Protein
Produktgrößen
10ug
£240,00
OPCD02745-10UG
50ug
£446,00
OPCD02745-50UG
200ug
£788,00
OPCD02745-200UG
Über dieses Produkt
- SKU:
- OPCD02745
- Zusätzliche Namen:
- dickkopf 1 homolog;dickkopf-1 like;dickkopf-like protein 1;dickkopf-related protein 1;DKK-1;SK.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development; where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning; limb development; somitogenesis and eye formation. In the adult; Dkks are implicated in bone formation and bone disease; cancer and Alzheimer disease (PubMed:17143291). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner; and has anti-apoptotic activity (By similarity).
- Gendetails:
- dickkopf WNT signaling pathway inhibitor 1
- Host:
- E. coli
- Molekulargewicht:
- 33kDa
- Proteindetails:
- Dickkopf-related protein 1
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php