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Proteine und Peptide

DISC1 Recombinant Protein

Produktgrößen
10ug
£272,00
OPCD02741-10UG
50ug
£528,00
OPCD02741-50UG
200ug
£955,00
OPCD02741-200UG
Über dieses Produkt
SKU:
OPCD02741
Zusätzliche Namen:
disrupted in schizophrenia 1 homolog.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis; including neuron positioning; dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role; together with PCNT; in the microtubule network formation.
Gendetails:
disrupted in schizophrenia 1
Host:
E. coli
Molekulargewicht:
25kDa
Proteindetails:
Disrupted in schizophrenia 1 homolog
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins