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Proteine und Peptide

CUBN Recombinant Protein

Produktgrößen
10ug
£279,00
OPCD02555-10UG
50ug
£539,00
OPCD02555-50UG
200ug
£977,00
OPCD02555-200UG
Über dieses Produkt
SKU:
OPCD02555
Zusätzliche Namen:
AA408369;AL022750;cubilin;D2Wsu88;D2Wsu88e;intrinsic factor-cobalamin receptor.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Cotransporter which plays a role in lipoprotein; vitamin and iron metabolism; by facilitating their uptake. Binds to ALB; MB; Kappa and lambda-light chains; TF; hemoglobin; GC; SCGB1A1; APOA1; high density lipoprotein; and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia; including intestine; renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC; hemoglobin; ALB; TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
Gendetails:
cubilin (intrinsic factor-cobalamin receptor)
Host:
E. coli
Molekulargewicht:
16kDa
Proteindetails:
Cubilin
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins