CD14 Recombinant Protein
Produktgrößen
10ug
£290,00
OPCD01982-10UG
50ug
£565,00
OPCD01982-50UG
200ug
£1031,00
OPCD01982-200UG
Über dieses Produkt
- SKU:
- OPCD01982
- Zusätzliche Namen:
- Myeloid cell-specific leucine-rich glycoprotein.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Coreceptor for bacterial lipopolysaccharide. In concert with LBP; binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex; thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88; TIRAP and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides; these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
- Host:
- E. coli
- Molekulargewicht:
- 41kDa
- Proteindetails:
- Monocyte differentiation antigen CD14
- Reinheit:
- >95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php