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Proteine und Peptide

CD14 Recombinant Protein

Produktgrößen
10ug
£322,00
OPCD01981-10UG
50ug
£652,00
OPCD01981-50UG
200ug
£1204,00
OPCD01981-200UG
Über dieses Produkt
SKU:
OPCD01981
Zusätzliche Namen:
CD14 antigen;monocyte differentiation antigen CD14;myeloid cell-specific leucine-rich glycoprotein.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Coreceptor for bacterial lipopolysaccharide. In concert with LBP; binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex; thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88; TIRAP and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides; these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (By similarity).
Gendetails:
CD14 molecule
Host:
E. coli
Molekulargewicht:
70kDa
Proteindetails:
Monocyte differentiation antigen CD14
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins