CCND1 Recombinant Protein
Produktgrößen
10ug
£235,00
OPCD01971-10UG
50ug
£435,00
OPCD01971-50UG
200ug
£766,00
OPCD01971-200UG
Über dieses Produkt
- SKU:
- OPCD01971
- Zusätzliche Namen:
- B-cell CLL/lymphoma 1;B-cell lymphoma 1 protein;BCL1;BCL-1 oncogene;D11S287E;G1/S-specific cyclin-D1;PRAD1;PRAD1 oncogene;U21B31.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3; phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex; cyclin D1/CDK4/CDKN1B; required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner.
- Gendetails:
- cyclin D1
- Host:
- E. coli
- Molekulargewicht:
- 63kDa
- Proteindetails:
- G1/S-specific cyclin-D1
- Reinheit:
- > 90%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php