ATP2A2 Recombinant Protein
Produktgrößen
10ug
£268,00
OPCD01540-10UG
50ug
£522,00
OPCD01540-50UG
200ug
£940,00
OPCD01540-200UG
Über dieses Produkt
- SKU:
- OPCD01540
- Zusätzliche Namen:
- ATP2B;ATPase Ca++ transporting cardiac muscle slow twitch 2;ATPase; Ca++ dependent; slow-twitch; cardiac muscle-2;calcium pump 2;Calcium-transporting ATPase sarcoplasmic reticulum type; slow twitch skeletal muscle isoform;cardiac Ca2+ ATPase;DAR;DD;endoplasmic reticulum class 1/2 Ca(2+) ATPase;sarcoplasmic/endoplasmic reticulum calcium ATPase 2;SERCA2;SR Ca(2+)-ATPase 2.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle (PubMed:16402920). Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca (2+) spiking for activation of NFATC1 and production of mitochondrial ROS; thereby triggering Ca (2+) signaling cascades that promote osteoclast differentiation and activation (By similarity).
- Gendetails:
- ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
- Host:
- E. coli
- Molekulargewicht:
- 78kDa
- Proteindetails:
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
- Reinheit:
- > 90%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php