ARG2 Recombinant Protein
Produktgrößen
10ug
£235,00
OPCD01478-10UG
50ug
£435,00
OPCD01478-50UG
200ug
£766,00
OPCD01478-200UG
Über dieses Produkt
- SKU:
- OPCD01478
- Zusätzliche Namen:
- arginase II;arginase; type II;arginase-2; mitochondrial;kidney arginase;kidney-type arginase;L-arginine amidinohydrolase;L-arginine ureahydrolase;nonhepatic arginase;non-hepatic arginase;type II arginase.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells (PubMed:27745970). May suppress inflammation-related signaling in asthmatic airway epithelium (PubMed:27214549). May contribute to the immune evasion of H.pylori by restricting M1 macrophage activation and polyamine metabolism (By similarity). In fetal dendritic cells may play a role in promoting immune suppression and T cell TNF-alpha production during gestation (PubMed:28614294). Regulates RPS6KB1 signaling; which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction (PubMed:22928666). Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling (PubMed:25484082). Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity (PubMed:23832324). Since NOS is found in the penile corpus cavernosum smooth muscle; the clitoral corpus cavernosum and the vagina; arginase-2 plays a role in both male and female sexual arousal (PubMed:12859189).
- Gendetails:
- arginase 2
- Host:
- E. coli
- Molekulargewicht:
- 44kDa
- Proteindetails:
- Arginase-2; mitochondrial
- Reinheit:
- > 90%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php